Medical News: Tumors Evolve Rapidly in a Childhood Cancer

— CHOP Researcher Leads Large, Multicenter Gene Sequencing Study of Neuroblastoma–

Newswise — Philadelphia, Jan. 20, 2013 –An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene mutations—mutations that would suggest new targets for neuroblastoma treatment. Instead, say the researchers, they have now refocused on how neuroblastoma tumors evolve in response to medicine and other factors.