Animal News: Rescue Puppy Named New Voice Of The TurfMutt Foundation

(NAPSI)—A puppy named Mulligan has big paws to fill, but the mixed breed rescue dog is up to the challenge of becoming the new voice for the TurfMutt Foundation, says his new owner and guardian, Kris Kiser, President of the organization.

Since 2009, Kiser’s rescue dog, Lucky, “pawed it forward” by leading the Foundation’s environmental education and stewardship program for students in grades K to 8. Sadly, Lucky passed away recently, but his superhero cape is being picked up by perky Mulligan, who was found by Kiser last month during Lucky’s Mutt Madness, a national pet adoption event organized by the Foundation during GIE+EXPO, the nation’s leading trade show for outdoor power, landscaping and hardscaping industry professionals, held each October in Louisville, Ky.

Mulligan was not the only rescue pup to find a new home. Fifteen other dogs from the Kentucky Humane Society also went home with new owners.

Carl Bennett and his family brought home a beagle mix puppy, named Jovial. “She is completely living up to her name. She’s happy and sweet and loves everyone. She’s very smart and is already learning tricks,” said Bennett.

Bennett admits they weren’t planning to bring a puppy home but added, “When we saw her sweet little face and floppy ears we all fell in love. We never expected to adopt but something told us she needed to be a part of our family.

A ten-year-old dog named Mama went home with Mark Potocki. He was concerned she wouldn’t get the love she deserved because she was older. “Once I had the chance to hold her, she curled up in my arms and my decision was made,” said Potocki.

He said Lucky’s Mutt Madness was a wonderful experience. “What a great event. The vibe of the afternoon was fun and drew attention to the need for pet adoption,” said Potocki.

Kiser is deep into puppy training for Mulligan. “As a spokesdog, TurfMutt has to visit schools, and sometimes goes with me for public appearances and on TV sets, so Mulligan needs to be well-socialized and know how to behave.”

“Mutt Mulligan” marks a new page in the TurfMutt platform, which grew from a youth education program launched in 2009 in a handful of Sacramento and Washington, D.C. schools to reaching 70 million students, teachers, and families with its message that everyone can help save the planet, starting with their backyard.

Kiser added, “People can understand the value of a living landscape, when they see it through the eyes of a dog. You suddenly realize that soft grass is kinder to paws than hard concrete and that you need shade and a variety of plants in your yard.”

The TurfMutt program has become a national platform, appearing on every major television network, The Hub, Animal Planet and more, including the award-winning show, “Lucky Dog,” for three seasons; being featured in Parade magazine’s Earth Day issue; and winning awards. TurfMutt is an official USGBC Education Partner and part of its global LEARNING LAB, and has been an education resource at the U.S. Department of Education’s Green Ribbon Schools, the U.S. Department of Energy, the U.S. Environmental Protection Agency, Green Apple, the Center for Green Schools, the Outdoors Alliance for Kids, the National Energy Education Development (NEED) project, Climate Change Live, Petfinder and the U.S. Fish and Wildlife Service.

More information on Lucky’s Mutt Madness event and the program is at

www.TurfMutt.com

.

Charlotte L. Bishop (75) of Gloucester Township, formerly of Gloucester City

On February 28, 2020.

Age 75.

(

nee

DeMore

)

Of Gloucester Township.

Formerly of Gloucester City.

Predeceased by her husband, Westley Bishop, Sr. Survived by her daughter, Anne Marie

Reimel

(

fiancé

Edward

Berckman

); grandchildren Melonie Margaret

Reimel

,

Adam Michael

Wentzel

, Victoria R.

Berckman

and

Dominique E. Francis (Nicholas J.)

P

redeceased by her son, Robert

Muzyczek

.

At the request of her family, cremation will be private. Memorial Services are being planned for a later date.

Memorial donations may be made to Msgr.

Lucitt’s

Needy Children’s Fund, PO Box 87, Gloucester City, NJ 08030. Please memo, Charlotte L. Bishop.

Condolences and Memories may be shared at

www.mccannhealey.com

under the obituary of Charlotte L. Bishop. Funeral Arrangements and Inquiries through:

McCANN

–HEALEY FUNERAL HOME, Gloucester City Ph

:856

-456-1142

VISTAs lend a helping hand in preparation for the FaithFULL Food Drive

CAMDEN CITY, NJ–A group of AmeriCorps VISTA (Volunteers in Service to America) who currently work at the Center For Family Services, volunteered their time and efforts at Catholic Charities’ headquarters in Camden City. There, they organized and sorted through items in preparation for the upcoming Camden Diocesan FaithFULL Food Drive on March 22. After the drive, Catholic Charities will use this space to temporarily store donated food items before distributing it to the agency’s other offices throughout Southern New Jersey to ensure that clients and those who are hungry will be given food and connected to the agency’s services.

To learn more about volunteer opportunities at Catholic Charities,

click here

, or to learn more about the upcoming FaithFULL Food Drive,

click here

.

Energy efficiency lighting rebate grants offered by DNREC

Available to businesses, local governments and non-profits

DOVER, Del. – Delaware organizations looking to reduce energy consumption and related costs through energy-efficient lighting now have expanded grant opportunities through Delaware’s Energy Efficiency Investment Fund (EEIF). Administered by DNREC’s Division of Climate, Coastal, & Energy, the fund

offers grants to offset the cost of energy efficiency improvements, and has broadened the kinds of light fixtures that will qualify for grants while adjusting incentives offered for large custom projects to reflect competitive regional market rates.

EEIF assists with energy assessments, lighting, HVAC, complex retrofits, building improvements, and thermal energy systems. Changes to the lighting incentives include 34 new categories of eligible fixtures, varying incentive rates based on wattage, and the addition of incentives for lighting control systems. All incentive levels also have been adjusted to reflect market conditions for LED lights.

Updates to comprehensive custom projects have been made to promote maximum energy efficiency efforts, including implementing a tiered system that encourages applicants to consider projects with multiple end-use benefits. The EEIF program is also creating its first incentives for reducing emissions, such as carbon dioxide (CO

2

).

“The EEIF program has been hugely successful supporting projects that saved over 55 million kilowatts in fiscal year 2019 alone,” said Dayna Cobb, director of the Division of Climate, Coastal, & Energy. “These additions to EEIF add even greater value to a program that is already reducing energy usage and pollution.”

EEIF is funded through the Public Utility Tax (PUT), the Regional Greenhouse Gas Initiative (RGGI) and one-time funding from the Exelon-Pepco merger settlement through which Delmarva Power, a major Delaware energy provider, became an Exelon company in 2016. Grant amounts are capped at 30 percent of the project’s total cost. Any application approved after Feb. 1, 2020 will reflect the new lighting and custom incentive levels.

For details on the program, application forms, and a list of eligible lighting products and rebates for deploying them, please visit

www.de.gov/eeif

.

A Little Girl from Indiana is Pursuing Her Dreams Thanks to Her New Kidney

March is National Kidney Month:

March 2, 2020

March is National Kidney Month, which is a month-long, awareness-raising grassroots effort to spread the word nationwide about the importance of kidney health. An Indiana transplant family knows all too well the life-saving difference a

healthy kidney can make.

Paula and David Check of Fishers, Indiana, remember the excitement of learning they were pregnant with their first child. Paula’s pregnancy was normal by all accounts and they were simply counting the days until their precious baby would be born. Baby Lydia arrived in December 2009 and the family of three felt complete. She was an adorable infant who grew into a toddler — her first years of life seemed ‘normal’ to both Paula and David.

But during the summer months of 2014 Paula noticed then four-year-old Lydia was becoming increasingly sick, tired and weak. By the fall months Lydia was vomiting and having diarrhea regularly. She began bleeding from her bowels. Paula remembers taking Lydia to the family doctor several times insisting there was something seriously wrong with their little girl. In January 2015 Lydia’s weight loss became incredibly noticeable; she was literally skin and bones. In February 2015 a gastro intestinal specialist diagnosed Lydia with Ulcerative Colitis, which meant she had bleeding ulcers in her stomach and colon. Eight months later in September 2015 it was determined Lydia also had a serious kidney issue that would require a kidney transplant for her long-term survival.

Lydia, with a little help from her mom, has written a narrative about her transplant journey. Here is how Lydia tells her transplant story to date:

Hello my name is Lydia, I am 10 years old, and the last six years have been really difficult. I have been sick since August 2014 with an autoimmune disorder. When I was younger I was weak, tired and had extreme weight loss. My parents took me to the doctor repeatedly, always telling him something was wrong. But my problem went undiagnosed until January 2015. That is when I began treatment for Ulcerative Colitis. After several doctor appointments and medications, it went into remission.

In August 2015 something was not right with my kidney function. Labor Day weekend I was admitted to Riley Hospital for Children and I had a biopsy performed. I spent the entire day in bed. I was required to lay flat on my back to prevent bleeding from the procedure. The next three days in the hospital I was given super strength IV steroids. I initially showed improvement from the steroids and was sent home on Labor Day afternoon. Steroids work great for some people but I was not showing signs of improvement — just the side effects of weight gain, a puffy face, lots of emotions and not being able to sleep through the night. In May 2016 a G Tube was placed in my belly so medications could go right to my tummy. An overnight drip of Pedialyte was started to keep me from dehydrating. Testing determined I have a genetic disease.

Lydia’s diagnosis, Nephronophthisis, is a

genetic disorder

of the

kidneys

that affects children. The disorder is inherited in an

autosomal recessive

fashion and, although rare, is the most common genetic cause of childhood kidney failure. Although the range of characterizations is broad, those kids affected by nephronophthisis typically produce a large volume of urine, drink excessive amounts of liquid, and after several months to years, develop

end stage renal (kidney) disease

— a condition necessitating either dialysis or a kidney transplant in order to survive.

As Lydia’s kidney disease progressed, Paula and David started meeting with the transplant team at Riley Hospital for Children. In January 2017, upon a transplant social worker’s urging, Paula called the Children’s Organ Transplant Association (COTA) to learn more about fundraising for transplant-related expenses. COTA is a 501(c)3 charity so all contributions to COTA in honor of Lydia are tax deductible to the fullest extent of the law, and COTA funds are available for a lifetime of transplant-related expenses. COTA uniquely understands that parents who care for a child or young adult before, during and after a life-saving transplant have enough to deal with, so COTA’s model shifts the responsibility for fundraising to a community team of trained volunteers. On February 24th Lydia became part of the COTA Family.

A COTA fundraising specialist travelled to Fishers, Indiana, on March 20th to train the family’s volunteers and walked them through the entire process. This group of family members and friends quickly got to work organizing fundraisers to help with mounting transplant-related expenses. According to Paula, COTA’s team of professionals was supportive, encouraging and very helpful every step of the journey.

Once we found out I needed a new kidney, several people started the testing process to see if they could be my living donor. Those tests were unsuccessful. In late 2017 I was approved to be on the national kidney waiting list. However my wait was long and in August 2018 I went from low kidney function to kidney failure.

That is when the doctors told us it was time to begin dialysis. Our family decided hemodialysis was the best choice and I went in for the surgery that would allow me to be on dialysis. During the first surgery I lost a lot of blood and needed a blood transfusion. Then they were unable to get the dialysis machine up to full speed during my first treatment. It was decided there was a problem with my central line and they needed to do surgery again. This time it worked. I was on dialysis four hours a day, three days a week. It was long and exhausting.

On August 31, 2018, right when we got home from dialysis, Mom got a phone call from Riley. They had a kidney match for me! It was an emotional roller coaster. I was happy. I was scared. I had no idea what to expect. The next day on September 1

st

, I received my new kidney and the transplant was a big success. Sixteen days later on September 17

th

I was released from the hospital to go home. Wow.

“I knew Lydia’s transplant surgery and follow-up care and medications and everything would be very expensive. Once we found COTA a huge stressor was lifted from our shoulders. If we had not been introduced to COTA our family would have been very lost during a time of tremendous need. COTA gave us the strength and direction we needed to get through a very challenging chapter in our family’s story,” Paula said.

“The Children’s Organ Transplant Association (COTA) gave us hope when we were feeling hopeless. COTA’s team of professionals were supportive and encouraging every step of the way. Knowing COTA funds are not just for the expenses leading up to a transplant but will be there throughout Lydia’s life is truly amazing. If we had not found COTA, we would have been lost during a time of tremendous need. COTA gives our family strength and direction, and will continue to do so …

for a lifetime

,” Paula said.

Lydia returned to Fall Creek Elementary and completed third grade with her new kidney. She also was able to return to her beloved dance classes at Wishes Dance Studio. When asked how life has been with her new kidney Lydia said, “I have done amazing things like riding on my very own float in the Fishers Spark Parade, running in a Super Hero 5K, going to my first Indiana Pacers game, and meeting Mickey & Minnie Mouse.” These days dancing remains at the top of the list of the things Lydia enjoys doing, but she also loves singing, pretending she is a Super Hero, cheerleading and meeting Disney princesses. She also loves to tell the story of her transplant journey.

Lydia’s new lease on life has allowed her to start dreaming about a future, which is the best gift Paula and David can imagine for their vivacious girl who has a huge smile and a huge heart. Lydia’s bucket list currently includes taking a Disney Cruise, seeing the Eiffel Tower in Paris, meeting Taylor Swift and having tea with the Queen of England.

In Lydia’s word, “Wow.”

March is designated National Kidney Month to raise awareness about the prevention and early detection of kidney disease. More than 30 million Americans have kidney disease, and many do not know it. There are more than 100,000 people waiting for kidney transplants, with close to 600,000 people in the United States suffering with kidney failure. More than 3,000 new patients are added to the kidney waiting list each month; 13 people die each day while waiting for a life-saving kidney transplant. Every 14 minutes someone is added to the kidney transplant list. You can visit

www.RegisterMe.org

to indicate your wish to be a life-saving donor.

For more information about the Children’s Organ Transplant Association (COTA),

or to find a COTA family in your area, please email

kim@cota.org

.

Annalise Jean Schultz, age 9, Of Moorestown

Moorestown – Annalise Jean Schultz, age 9, passed away peacefully, after a courageous 8-month battle with brain cancer, at Children\’s Hospital of Philadelphia (CHOP) on February 26, 2020. She was born on May 24, 2010 to Chad and Jennifer

(Schock) Schultz and lived a vibrant life in Moorestown, NJ. She was adored by her younger brother, Sebastian. She was the beloved granddaughter of David Schultz, Catherine Schultz, John Schock, and Elaine Schock (Tom Plunkett). She will always be remembered by her loving aunts, uncles and cousins. Annalise was the heart of her family, and the life of all the parties—organizing games, putting on shows, taking pictures and making everyone laugh.

Annalise attended Mary E. Roberts Elementary from Kindergarten-3rd grade, where she was recognized for her kindness and grit. She enjoyed Reading, Social Studies and Art. She spent countless recesses playing gaga, sitting on the Buddy Bench with a friend, jumping rope, or studying worms. She loved Girl Scouts, basketball, softball, playing with her dog, hula-hoop and swimming. She will forever be remembered for her love of pandas and the music of Bob Marley, but also her love for learning magic tricks, telling jokes, playing music (recorder & piano) and her insatiable curiosity for everything from US presidential history to the legendary Bigfoot.

Annalise\’s battle with a rare pediatric brain tumor, Diffuse Midline Glioma (DMG), began in the summer of 2019, prior to starting 4th grade at her new school, Moorestown Upper Elementary School. Teachers and students welcomed her with open arms, and while she only attended school briefly, she was a proud UES Tiger.

Annalise\’s beautiful, contagious smile will be missed by her family, countless friends, teachers and all in her community and beyond.

Relatives, friends and the Moorestown Community are kindly invited to attend Annalise\’s visitation on Thursday, March 5 from 5 pm to 8 pm and Friday, March 6 from 9:15 am to 10:45 am at St. Matthew\’s Lutheran Church: 318 Chester Avenue, Moorestown, NJ 08057. Lutheran Service 11 am in the church. Burial private.

In lieu of flowers, memorial donations can be made to the Childhood Brain Tumor Tissue Consortium Fund (

cbttc.org

) at Children\’s Hospital of Philadelphia 3401 Civic Center Blvd Philadelphia, PA 19104. Please write in memo: Annalise Schultz.

Visit

AmazingAnnalise.com

to read her story or donate to Annalise\’s memorial fund.

Condolences and Memories may be shared at

www.mccannhealey.com

under the obituary of Annalise Jean Schultz. Funeral Arrangements and Inquiries may be made through: McCann-Healey Funeral Home: Gloucester City. Ph:

856 – 456 – 1142

Camden County Employee Charged with Theft

Camden, N.J. – A Camden County employee has been charged with stealing more than $114,000 that was intended for regattas and rowing competitions at Cooper River Park, according to Acting Camden

County Prosecutor Jill S. Mayer.

James Stack, 44, of Collingswood, has been charged with Theft by Failure to Make Required Disposition of Property Received and Official Misconduct.

Investigators say Stack, who previously served as the Director of Rowing at the Camden County Boathouse, accepted money from various rowing organizations and deposited the checks into two bank accounts he managed under Cooper Training Center, LLC, a company Stack owns. Detectives said evidence showed Stack would then deposit a lesser amount into accounts managed by the county.

The discrepancy was caught during a county audit and reported. Investigators found evidence dating back to January 2018 through December of 2019 and said the investigation is ongoing.

Stack was cited and released pending a Central Judicial Processing hearing March 10.

All persons charged with crimes are presumed innocent until proven guilty in a court of law.

1000\’s Attend St. Mary\’s/ Gloucester City Irish Parade (photos)

by CNBNews Staff

GLOUCESTER CITY, NJ (March 3, 2020)–This year\’s parade, held Sunday, March 1, was \”much bigger than last year\”, said Mayor Dan Spencer. \”Between all the marchers and spectators it was estimated upwards of 5,000 people in town.\’\”

Spencer said, \”I would like to extend my appreciation to all of our parade sponsors especially the Camden County Board of Chosen Freeholders, all of our great city employees from the Public Works Department, Police and Fire Departments, Camden County Special Events Department, Msgr. William Hodge from St. Mary’s, Charlie Kain, President of the New Jersey Irish Society, Tom Gurick our MC, Bob Kelly from Fox 29 News, Principal Ed Beckett our Grand Marshall from Gloucester Catholic High School, Dr. Dennis Vespe and Principal Sean Gorman from the Gloucester City School District for all their support, Members of City Council, my friends from the Philadelphia Mummers String Band Association for their help and support in organizing things on parade day, and all of those who had anything to do with making this a bigger and better event for putting Gloucester City in the spotlight. We are happy for the many people who visited our businesses that day, especially those who visited our taverns and restaurants. I apologize for anyone I forgot, so a GREAT BIG THANK YOU TO EVERYONE, Especially the great citizens of Gloucester City for being so humble and hospitable. See you next year for an even bigger and better parade.\”

( photos courtesy of Heidi Weaver heidiho7272@gmail.com )

The opening ceremony of the parade began in front of the church with Sheila McGirl singing  the anthems as the flags for the United States and Ireland were raised by Assemblyman Bill Moen. Grand Marshall Ed Beckett and Deputy Consul General from Ireland Sean O\’Hageon look on

The Brian Boru Pipes and Drums Band with Kevin Flatley Drum Major parades by St. Mary\’s  Church

Several thousand people attended this year\’s parade. Gloucester City Mayor Dan Spencer was decked out in his Irish scarf, tie and carried his Irish shillelagh

Gloucester City Mayor Dan Spencer and Monsignor Bill Hodge do their impression of the mummer strut with one of the string band captains in front of St. Mary\’s Church

Monsignor Bill Hodge enjoyed the day. Being the Irishman that he is he couldn\’t contain himself when the music starting playing he had this urge to strut his stuff.

Celebrity Parade Marshall Bob Kelly from Fox 29 was dressed out in his finery including his shamrock sports coat which he only wears, hopefully, at St. Patrick\’s celebrations.  Where do you buy something like that Bob?

Mary Blackiston just couldn\’t help herself. She showed everyone that you can\’t keep a Gloucester City girl down when the string band starts playing you have to dance!

Honor guest  Deputy Consul General from Ireland Sean O’Hageon

Ladies AOH State Officers Roseann Michel and Maread Gallagher

CLICK ON PHOTO TO ENLARGE

( photos courtesy of Heidi Weaver heidiho7272@gmail.com )

PA Legislators Concerned With $100M Redesign of State College System

By Christen Smith |

The Center Square

Gloucestercitynews.net files

Pennsylvania lawmakers questioned a proposed $100 million redesign of its higher education system this week after years of declining enrollment left many of its 14 universities in the red.

Pennsylvania State System of Higher Education (PASSHE) Chancellor Dan Greenstein said the “radical” plan – which includes a $20 million boost annually in state funding over the next five years – would allow the organization to share services, demolish underutilized buildings and encourage staff retirements that altogether could save between $80 million and $120 million through 2025.

“The universities have created five-year plans which demonstrate how they will balance the budgets from which these numbers are derived,” he told the Senate Appropriations Committee during PASSHE’s budget hearing this week. “And they will be held accountable for this. … This can has been kicked down the road, and the road has ended.”

Gov. Tom Wolf’s $36.1 billion state budget proposal allocates $490 million to PASSHE and $12.9 million in support of the system’s redesign effort. Greenstein said the agency needs a 2 percent increase over last year’s funding, plus the $20 million appropriation, to target its joint goals of keeping tuition affordable and the five-year redesign plan.

Greenstein said PASSHE also renegotiated labor union contracts and created an extended sick leave payout program the agency hopes will encourage 200 staff and faculty to retire annually. In October, all universities implemented “sustainability policies” that establish balanced budgets and new procedures meant to effectively manage personnel – from curtailing the use of temporary faculty to consolidating existing roles at all levels to eliminating or combining duplicative programs with low enrollment.

“It’s going to require an unprecedented level of collaboration with our unions and close collaboration with our universities,” Greenstein said. “This will stretch us, but I am confident we are ready, and as the numbers portray, it is time.”

Enrollment across PASSHE’s 14 universities declined 20 percent over the past decade, Greenstein said, while state funding levels for the system rank 47th nationwide. Pennsylvania’s student debt is also the second highest in the nation, Greenstein added, despite the agency’s priority of keeping tuition affordable.

“You and all the students have the absolute right to be enraged and livid by the lack of leadership from this General Assembly,” said Sen. Steve Santarsiero, D-Bucks. “The fact is that we are not investing where we should be investing. We are not giving you the resources you need.

“The cost that our students are asked to bear, as you just said, has a direct relationship with the funding we give to our state system” he added. “It’s inexcusable that Pennsylvania ranks 47th in the country.”

Other senators pressed Greenstein on whether the redesign plan should consider closing universities with lower attendance rates – an idea the chancellor said disenfranchises the rural communities many of them serve.

“I don’t think the numbers support your theory because the rural institutions are the ones that had the greatest reduction in numbers,” said Sen. Gene Yaw, R-Lycoming. \”I know how important Mansfield University is to the town of Mansfield, … but somewhere along the line, we really have to take a look at would we be better off closing them and folding the funding into the institutions that are really thriving.”

Sen. Scott Martin, R-Lancaster, told Greenstein the “backwards” prioritization of struggling universities concerns him and undermines the few schools that remain successful.

“My big worry, from many different perspectives, is the fact that we are missing out on opportunities with the institutions that are growing, that are doing their best to keep their head above water and that they cannot do these things because they’re not getting the resources,” he said. “The resources are being funneled through back channels to create opportunities that every single student in the commonwealth is not being given, in terms of scholarships, and that’s just fundamentally not fair.”

Martin’s comments reference Wolf’s $204 million proposed Nellie Bly Tuition Program, which would target financial assistance to full-time PASSHE students. Under program rules, students must agree to stay in Pennsylvania for as many years as they received the benefit.

Senate Education Committee Minority Chairman Andy Dinniman, D-Chester, criticized the scholarship program proposal during Thursday’s hearing, insisting that raiding the Pennsylvania Race Horse Development Trust Fund would only result in court challenges the state is certain to lose.

\”I wish it was as simple as we’ve said,\” he said. \”If you try to take the money out … and to play this game of letting students think they will get these scholarships and they will not, because it will go to court.\”

published by Gloucestercitynews.net with permission of

The Center Square

Temple’s Dr. Silvia Fossati Awarded $500,000 Grant for Alzheimer’s Disease Drug Discovery Research

(Philadelphia, PA) – Silvia Fossati, PhD,

Associate Professor of Pharmacology and Associate Director of the Alzheimer’s Center at Temple at the Lewis Katz School of Medicine, has been awarded a two-year $500,000 grant from The Edward N. and Della L. Thome Memorial Foundation, Bank of America, N.A., Trustee, as part of the Foundation’s Awards Program in Alzheimer’s Disease Drug Discovery Research.

Dr. Fossati, the principal investigator on the grant, will work with co-investigator

Marc Ilies, PhD,

Professor in the Department of Pharmaceutical Sciences at the Temple University School of Pharmacy, to develop a new Alzheimer’s-specific version of an already-existing drug family called carbonic anhydrase inhibitors, which are approved by the U.S. Food and Drug Administration (FDA) to treat conditions such as glaucoma and high-altitude sickness.

Previous studies in Dr. Fossati’s Lab showed that these drugs were effective in cell and animal models at targeting certain features of Alzheimer’s disease, including mitochondrial dysfunction, amyloid protein build-up, and inflammation.

Research has suggested that chronic inflammation in the brain may be due to the build-up of cells that normally free the organ of debris, waste and protein collections – including amyloid protein. When amyloid protein deposits in abnormal levels in the brain, it can disrupt cell function and communication pathways. Elevated levels can also be a factor in abnormalities of the mitochondria – the energy-generating batteries of cells – and in damaging the brain vasculature (its blood vessels). Collectively, these can eventually contribute to cognitive dysfunction, including impairments in memory and learning – hallmarks of Alzheimer’s disease.

Ideally, Dr. Fossati and Dr. Ilies’ drug would target these characteristics, as currently available carbonic anhydrase inhibitors do, but would better infiltrate the brain and cause fewer side effects.

The drug would be tested in cell and animal models of Alzheimer’s disease first and then potentially in human clinical trials in two to three years.

“Since carbonic anhydrase inhibitors have already been approved by the FDA and have demonstrated promising results, we are hopeful that we will be able to tailor what is currently available on the market to specifically target Alzheimer’s disease,” Dr. Fossati said. “We are so thankful that the foundation sees such promise in our work and has chosen to recognize us with this grant.”

The Edward N. and Della L. Thome Memorial Foundation, Bank of America, N.A., Trustee, which was established in 2002 by Robert P. Thome to honor the memory of his parents, provides funding in two areas – support for the dignified treatment of older adults and support for medical research on diseases affecting older adults. The medical research division alternates between funding research on macular degeneration and Alzheimer’s disease.

About Temple Health

Temple University Health System (TUHS) is a $2.2 billion academic health system dedicated to providing access to quality patient care and supporting excellence in medical education and research. The Health System consists of Temple University Hospital (TUH)

;

TUH-Episcopal Campus; TUH-Jeanes Campus; TUH-Northeastern Campus; The Hospital of Fox Chase Cancer Center and Affiliates, an NCI-designated comprehensive cancer center; Temple Transport Team, a ground and air-ambulance company; Temple Physicians, Inc., a network of community-based specialty and primary-care physician practices; and Temple Faculty Practice Plan, Inc., TUHS’s physician practice plan comprised of more than 500 full-time and part-time academic physicians in 20 clinical departments. TUHS is affiliated with the Lewis Katz School of Medicine at Temple University.

Temple Health refers to the health, education and research activities carried out by the affiliates of Temple University Health System (TUHS) and by the Katz School of Medicine. TUHS neither provides nor controls the provision of health care. All health care is provided by its member organizations or independent health care providers affiliated with TUHS member organizations. Each TUHS member organization is owned and operated pursuant to its governing documents.

It is the policy of Temple University Health System that there shall be no exclusion from, or participation in, and no one denied the benefits of, the delivery of quality medical care on the basis of race, ethnicity, religion, sexual orientation, gender, gender identity/expression, disability, age, ancestry, color, national origin, physical ability, level of education, or source of payment.