Different Types of Online Gambling Sites

(Gloucestercitynews.net)(March 11, 2020)–Online gambling today is part of our everyday lives. Thanks to the higher rates of internet penetration and an increased number of smartphone users, everyone can play games of chance online. Even the governments see the benefits of online gambling and a greater number of countries have

since

legalized and allow online gambling

.

If you’re new to the world of online gambling, you’ll likely feel overwhelmed by the huge number of gambling sites, and games. Hence, it is probably a good idea to familiarize yourself beforehand with the types of online gambling and their difference. In our article, you can read more about the most popular types of online gambling sites.

Online Bingo Sites

There are many reputable online bingo sites like

Wink Bingo

that offer bingo games online. It’s good to know that there are a couple of different versions of bingo such as 80-ball, 90-ball, 75-ball bingo and

30- ball bingo. You’ll find they are pretty similar, and regardless of the type you chose to play, the objective of the game is to mark the numbers as they are being drawn.

Unlike the game in the real world, online a random number generator is used to pick the numbers. Also, on most online bingo sites you will find a chat feature that allows you to interact with other players. This is an important component for many players that love to socialize while they play and it also builds a sense of community around the game. It’s also worth mentioning, that bingo is a game of pure luck so have fun while you play various bingo games online and connect with other players.

Online Casino Sites

On most online casino sites, you will find casino games like slots, roulette, poker, blackjack in many variants. In fact, you will have access to a vast selection of casino games, sometimes in a greater number than in a traditional casino. Another advantage of playing casino games online is the opportunity to play some of the casino games in free mode.

Furthermore, on online casino sites as a new player, you will access to a lot of exciting bonuses and promotions like free spins, welcome bonuses, and rewards. When you’re playing online casino games is good to know that some casino games require a certain level of skill and knowledge. Games like blackjack, baccarat, craps, poker are skill-based casino games and most of them are considered as casino games with the highest payouts.

Online Sports Betting Sites

In

online sports

betting, you are placing a bet on the outcome of an upcoming sporting event. For example, you might place your bet on Chelsea beating Arsenal in a football match. According to the result of the game, you will win a profit based on the bookmaker odds or lose the wager.

On online betting sites, there is information about the event, what kind of bets can be placed, and what you can win. The diversity and number of sporting events to choose from are one of the reasons why this form of gambling appeals to a wide audience around the world.

Online Poker Sites

Poker is one of the most popular gambling games. After all, there are whole tournaments and competitions dedicated solely to poker and in many traditional casinos, there are separate poker rooms. When you play the game online, you will have access to many opportunities to learn more about the poker, improve your skills and test different poker strategies. However, you should always keep in mind that all casino games still incorporate an element of luck which also has an influence over the end result of the game.

image source unsplash.com

Bernie Sanders Receives Endorsement from Working Families

The Working Families Party today announced its endorsement of U.S. Sen. Bernie Sanders (I-Vt.) in the Democratic primary for President of the United States and pledged to marshall its membership and grassroots power to help Sanders win the primary and defeat Donald Trump. The WFP had previously backed U.S. Sen. Elizabeth Warren (D-Mass.) in the Democratic primary, and was among her most significant backers.

The WFP will work to show voters who backed Warren why supporting Sanders is their best choice to advance the big structural change that Warren fought for. The WFP is planning an organizing call tonight at  8 p.m. ET for Warren supporters to speak to each other about their experiences on the campaign and next steps for progressives in 2020. Joining the call will be elected officials who had endorsed Warren but will now back Sanders for the nomination. WFP also announced plans to organize community meetings around the country to reach out to voters who were inspired by Warren’s run.

The WFP will mobilize members and supporters to vote for Bernie in upcoming primary states, including key contests tomorrow, as well as in primaries to come in states with strong WFP chapters, like Wisconsin, New York, Pennsylvania, and Connecticut.

“Bernie Sanders will fight for a Green New Deal, universal health care and a living wage for every worker. Organized capital won’t rest and neither will we,” said Maurice Mitchell, Working Families Party National Director. “We said from the very beginning that there were two progressive champions in this race, and that our North Star was to elect one of them as president. Now, the Working Families Party will marshall its grassroots supporters and staff to help Senator Sanders win the nomination and defeat Donald Trump.”

The WFP conducted an endorsement process last September using a ranked-choice voting system. While Warren came in first, Sanders finished a strong second, and the vast majority of members who supported Warren listed Sanders as their second choice. With Sen. Elizabeth Warren’s exit from the field, the WFP’s choice is clear. With so much at stake in the Democratic primary and the general election in November, WFP refuses to remain on the sidelines.

During Sanders’ Live Q&A with WFP in South Carolina last year, he vowed to break up big banks that contributed to the housing crash that saw working families lose their homes. Sanders also pledged to invest heavily in affordable housing, strengthen the power of unions and fight for a Green New Deal in his first term. In the 2016 Presidential election, the Working Families Party was one of Bernie Sanders’ earliest and most enthusiastic backers.

“We were lucky to have two strong progressives in this race who changed the conversation and shifted the limits of the possible,” said Working Families Party Director of Strategy and Partnerships Nelini Stamp. “There is no waiting for next time, because working class families and marginalized people can’t wait for next time. Climate change won’t wait, spiraling inequality won’t wait, and white supremacy won’t wait. Bernie Sanders is our best chance of making this a country that works for the many, not the few.”

The differences between Sen. Sanders and Vice President Biden are stark. The vice president’s past positions like the ‘94 crime bill, support for the Iraq war and support for the bankruptcy “reform” bill are at direct odds with the values and policies many WFP members and leaders fight for. For them, Biden represents a return to a time that disrupted families and upended lives.

“We must beat Donald Trump, but beating Donald Trump isn’t enough to win the world working families need and deserve,” said Andrea Serrano, Executive Director of OLÉ, New Mexico Working Families Party Co-Chair. “Bernie Sanders has been a life-long champion for working people, and he is our best chance to make the plans that Elizabeth Warren championed in her run a reality. But we won’t stop there. In addition to electing Senator Sanders, we are committed to fighting the misogyny we saw on display in the 2020 election, starting by electing a wave of progressive women up and down the ballot this year.”

The Working Families Party is a grassroots progressive political party that fights to make our country work for the many, not just the few. WFP recruits, trains, and elects the next generation of progressive leaders to office. The WFP has state chapters or local branches in seventeen states, and membership in every part of the country.

Last year the WFP drove a

progressive wave

in local elections across America. WFP member

Kendra Brooks

, won a citywide council seat to become Philadelphia’s first-ever third-party city councilor. WFP also helped to elect longtime tenants organizer and progressive champion Jumaane Williams as Public Advocate in

New York City

, swelled the ranks of

Chicago

city council progressive caucus, put public education champions on the school board in

Milwaukee

, helped make Stephen Mason the first Black mayor of

Cedar Hill

, Texas, helped insurgent Latinx LGBTQ activist Candi CdeBaca oust a longtime incumbent on the

Denver City Council

, and elected other council members from

Morgantown

, W.Va., to Phoenix, Ariz.

Atlantic City Electric Continues Efforts to Raise Awareness of Customer Scams

During National Consumer Protection Week

National Consumer Protection Week brings attention to common scamming practices and educates customers on how they can fight back and protect

themselves

MAYS LANDING, N.J.

(March 3, 2020) – Atlantic City Electric this week joins Utilities United Against Scams (UUAS) to recognize National Consumer Protection Week and to educate customers on how they can guard against falling victim to imposter utility scams.

As a member of UUAS—a consortium of 146 U.S. and Canadian electric, natural gas and water companies and their respective trade associations—Atlantic City Electric and its sister Exelon companies, Delmarva Power, BGE, ComEd, PECO and Pepco, work across the industry with regulators, law enforcement, and telecommunications partners to stop scams targeting customers.

“Nothing is more important than the safety of our customers, communities and our employees, and   we are committed to equipping our customers with the information and resources they need to protect themselves from scammers,” said Derrick Dickens, senior vice president of Customer Operations and Chief Customer Officer for Pepco Holdings, which includes Atlantic City Electric. “National Consumer Protection Week provides us with an important opportunity to continue these efforts and work with our partner organizations through Utilities United Against Scams to broaden our awareness efforts to combat the utility scamming that continues to target our customers.”

UUAS and its member companies continue to create awareness of common and new scam tactics and, to date, have helped to cease operations of more than 6,000 toll-free numbers used against utility customers by scammers.

When scams occur, a customer typically receives an unsolicited phone call from an individual, who falsely claims to be a company representative. The scammer often warns that the customer’s service will be terminated if they fail to make a payment – usually within a short timeframe through a prepaid debit card or other direct payment method.

Scammers have even duplicated the telephone systems of some companies, so when customers call the number provided by the scammer, it sounds like a legitimate business. Some scammers also use caller ID “spoofing” to replicate a company’s phone number.

Throughout the year, Atlantic City Electric takes steps to raise awareness among its customers, including posting tips to social media, adding alerts on the

AtlanticCityElectic.com homepage

, issuing news releases, and participating annually in

Utilities United Against Scams Day

in November. Any customer who believes he or she has been the target of a scam is urged to contact their local police and call Atlantic City Electric immediately at 800-642-3780 to report the situation.

Signs of Potential Scam Activity:

The scammer often becomes angry and tells a customer his or her account is past due and service will be shut off if a large payment isn’t made – usually within less than an hour.

The scammer instructs the customer to purchase a prepaid debit or credit card – widely available at most retail stores – then call him or her back to make a payment.

The scammer asks the customer for the prepaid card’s receipt number and PIN number, which grants instant access to the funds loaded to the card.

The scammers may disguise themselves as the utility by sending spam emails with logos, trademarks, website links, and wording to lure the customer into making a false payment or providing personal information.

How Customers Can Protect Themselves:

Atlantic City Electric representatives will never ask or require a customer with a past due balance to purchase a prepaid debit card to avoid disconnection.

Customers can make payments online, by phone, automatic bank withdrawal, mail, or in person.

Customers with a past due balance will receive multiple shut off notifications – never a single notification one hour before disconnection.

If a customer ever questions the legitimacy of the call, hang up and call Atlantic City Electric at 800-642-3780.

Don’t Get Scammed: Customers can avoid being scammed by taking a few precautions:

Never provide your social security number or personal information

to anyone initiating contact with you claiming to be a company representative or requesting you to send money to another person or entity other than Atlantic City Electric.

Always ask to see a company photo ID

before allowing any Atlantic City Electric worker into your home or business.

Never make a payment for services to anyone coming to your door.

Readers are encouraged to visit

The Source

,

Atlantic City Electric’s online news room. For more information about Atlantic City Electric, visit

atlanticcityelectric.com

. Follow the company on Facebook at

facebook.com/atlanticcityelectric

and on Twitter at

twitter.com/acelecconnect

.

Our mobile app is available at

atlanticcityelectric.com/mobileapp

.

2020 Household Hazardous Waste Collection Events

The Camden County Board of Freeholders is proud to present the 2020 Household Hazardous Water Collections. All collection hours are 8:30 AM to 3 PM rain or shine. These events are for Camden County residents only – no businesses accepted. Call (856) 858-5241 for more information. All Events are Rain or Shine.

MARCH 21 – CHERRY HILL PUBLIC WORKS COMPLEX

1 Perina Boulevard, Cherry Hill

APRIL 25 – COLLINGSWOOD PUBLIC WORKS CPLX

713 N. Atlantic Ave., Collingswood

MAY 16 – ATCO PARKING AREA

Corner of ATCO AVE. & RARITAN AVE.

JUNE 13 – GLOUCESTER TWP. – CAMDEN COUNTY COLLEGE

Parking Lot off of Peter Cheeseman Road

SEPTEMBER 26 – PENNSAUKEN SANITARY LANDFILL,

9600 N. River Road, Pennsauken

OCTOBER 17 – LINDENWOLD – CAMDEN COUNTY PUBLIC WORKS COMPLEX

2311 Egg Harbor Road, Lindenwold

Cherry Hill Public Works

1 Perina Boulevard, Cherry Hill, NJ, United States

Saturday, Mar 21st, 2020 @ 8:30 am

3:00 pm

Morristown Investment Adviser Who Breached His Fiduciary Duty to Customers Fined

Summary Penalty & Revocation Order

NEWARK – Attorney General Gurbir S. Grewal and the Division of Consumer Affairs announced today that the New Jersey Bureau of Securities revoked the registration of a Morristown investment adviser representative and assessed $750,000 in civil penalties for selling more than $12 million of unregistered securities in New Jersey, including investments tied to Ponzi schemes and other fraudulent investment scams.

Gary Scheer, managing member and sole investment adviser representative of Retirement Financial Advisors, LLC in Morristown, recommended and sold unregistered securities in seven different investments to at least 50 investors from 2010 through 2018. The sales generated more than $600,000 in commissions for Scheer.

Six of the seven investments Scheer recommended ultimately were determined by federal and/or state authorities to be fraudulent. As a result of Scheer’s conduct, investors were defrauded of their hard-earned savings.

In the Summary Penalty and Revocation Order (“the Order”) issued by the Bureau today, the Bureau Chief found that Scheer breached his fiduciary duty and violated the New Jersey Securities Law.

“Investment advisers are expected to serve the interests of their customers with undivided loyalty, and not exploit them for financial gain,” said Attorney General Grewal. “We will not allow unscrupulous professionals to undermine the integrity of New Jersey’s financial industry by enriching themselves at the financial expense of their customers.”

Scheer recommended and sold the unregistered securities while working as a representative for several investment advisers over an eight year period. The underlying investments in the unregistered securities included franchises, pension income streams, real estate development, and mortgages.

To date, all but one of the unregistered securities have been identified as investment frauds. For example, Scheer steered his customers into the unregistered “Woodbridge Securities,” which is alleged to be a $1.2 billion Ponzi scheme that defrauded 8,400 real estate investors nationwide, and the unregistered “Northridge Securities,” an alleged fraudulent “fix-and-flip” real estate investment whose principal and entities were recently charged by the U.S. Securities and Exchange Commission as running a $47 million Ponzi scheme.

According to the Order, Scheer violated the law by, among other things:

selling unregistered securities;

acting as an unregistered agent in the sale of those securities;

omitting or making material misrepresentations of the risks associated with the investments;

breaching his fiduciary duty by failing to conduct adequate due diligence before making the investment recommendations; and

breaching his fiduciary duty by failing to disclose significant conflicts of interest that were created by virtue of the undisclosed commissions being paid to him.

Scheer continued to advise customers to purchase unregistered securities even after he became aware that prior unregistered securities he recommended had come under regulatory scrutiny due to the issuers’ failures to register their securities and their fraudulent conduct, according to the Bureau’s findings.

“Scheer’s conduct represents an egregious breach of the fiduciary duty he owed to his customers,” said Paul R. Rodríguez, Acting Director of the Division of Consumer Affairs. “His actions resulted in serious financial consequences for investors, who are now left with the devastating impact of trying to recover their investments.”

Investor restitution efforts are underway by many of the federal and/or state authorities that brought the underlying enforcement actions against the issuers of the fraudulent securities Scheer sold.

“Investors must be able to trust that the investments they are sold are legitimate. Their investment professionals have a duty to conduct reasonable due diligence before making a recommendation,” said Christopher W. Gerold, Chief of the Bureau of Securities. “The Bureau of Securities will continue to aggressively enforce New Jersey’s Securities Laws against investment professionals that fail to fulfill their duties to their customer by selling unregistered and/or fraudulent securities.”

The Bureau’s investigation was handled by Deputy Bureau Chief Amy Kopleton, and Investigator Delfin Rodriguez.

Assistant Attorney General Brian F. McDonough, Deputy Attorney General and Section Chief Victoria Manning, and Deputy Attorney General Nicholas Dolinsky of the Securities Fraud Prosecution Section in the Division of Law represented the Bureau in this matter.

The Bureau is charged with protecting investors from investment fraud and regulating the securities industry in New Jersey. It is critical that investors \”Check Before You Invest.\” Investors can obtain information, including the registration status and disciplinary history, of any financial professional doing business to or from New Jersey, by contracting the Bureau toll-free within New Jersey at 1-866-I-INVEST (1-866-446-8378) or from outside New Jersey at 973-504-3600, or by visiting the Bureau\’s

website

. Investors can also contact the Bureau for assistance or to raise issues or complaints about New Jersey-based financial professionals or investments.

Gloucester Catholic\’s Philanthropy Week

x

Announcing our 3rd Annual Philanthropy Week! In 3 weeks, March Madness returns to Gloucester Catholic. Your support of #OurWeekForGC makes a profound difference. Starting March 23rd, it\’s your chance to show pride and gratitude for the impact that GC has on each of us. We thank you in advance.

VENMO

@gcramsgiving

ONLINE

http://gchsrams.org/wordpress/?p=10085

TRADITIONAL MAIL

Kindly make check payable to:

Gloucester Catholic High School

333 Ridgeway Street

Gloucester City, NJ 08030

Memo PW 2020

Top Gambling Apps for Windows 10

Gloucestercitynews.net (March 4, 2020)–From the second that online casino became a part of our lives, the game was changed forever. Before that, our favorite pastime was watching sports or something like that. Introducing

real money online gambling

into people’s lives had that same impact on humans as if one would give bears a life supply of honey. Your favorite amusement had become instantly accessible and an integral part of your life.

Advantages of PC casino games

No one would trade places with those old school players who visited gambling joints with a

solid reputation

if they were lucky to pick one. Those romantic days of rounders are gone as nothing can compare with that coziness of your comfy chair as one browse through his favorite game catalog. Crowded plus smokey rooms filled with angry or frustrated customers who had a bad luck streak is something one doesn’t need to put up with anymore. He can choose when or where he puts his chips and can take his break anytime, knowing that his earnings are secured plus guaranteed by trusted institutions. The virtual world of gaming is taking over, so take a seat in that front row hence enjoy your ride.

Top PC games

Slots Pro

This little application brings that touch of pro-slots straight onto your desktop. Choose between several themes set in the Victorian age, ancient Greece or tropical jungle. It comes in multiple languages with a size of fewer than two hundred megabytes. One can track his stats compared with players worldwide who also downloaded this charming app to enjoy

best slots

.

AE Blackjack Online

Practice makes it perfect, which is certainly true regarding blackjack gameplay. For getting your skills sharpened, try this online simulator which is very stylish but also informative for younger players eager to hone their skills. It is just over fifteen megabytes in size, plus one gets free one hundred credits every hour to continue the fun.

Microsoft Jackpot

This interactive slot adventure is made for younger audiences to get familiar with slots gameplay dynamics. Several cartooney themes provide visual delight which relaxes players as they immerse themselves into the roleplay. One can purchase play coins plus unlock achievements in this casual, lighthearted title, which is basically a community-driven experience.

Zynga Poker — Texas Holdem

This title brings back some happy memories as it represents a revolution in casual tournament poker play. What started as an extension of hanging on Facebook with your friends had become some worldwide phenomenon. With millions of players interlinked in this virtual jungle, poker enthusiasts can enjoy any kind of tournament setting as they please.

Simons Slots

This five-reel old-school retro slot fest is meant to induce some nostalgia for that time when first slot games hit the streets. Choose between multiple retro themes plus enjoy features like exchanging credits with your buddies or claiming new ones every few hours. It is constantly updated, plus it is small in size hence easily installed.

Conclusion

This casual world of free gambling applications is some great starting point to get familiar with most wanted games in some safe plus cozy environment. It allows young players to learn those basics before entering that world of real cash entertainment. Once equipped with a solid understanding of game dynamics, they will be ready for some serious action afterward.

This wearable device camouflages its wearer no matter the weather

The wearable thermal camouflage device is embedded in an armband and blends with the ambient temperature.

« This wearable device camouflages its wearer no matter the weather

Newswise — Researchers at the University of California San Diego developed a wearable technology that can hide its wearer from heat-detecting sensors such as night vision goggles, even when the ambient temperature changes–a feat that current state of the art technology cannot match.  The technology can adapt to temperature changes in just a few minutes, while keeping the wearer comfortable.

The device, which is at the proof-of-concept stage, has a surface that quickly cools down or heats up to match ambient temperatures, camouflaging the wearer’s body heat. The surface can go from 10 to 38 degrees Celsius (50 to 100.5 degrees Fahrenheit) in less than a minute. Meanwhile, the inside remains at the same temperature as human skin, making it comfortable for the wearer. The wireless device can be embedded into fabric, such as an armband. A more advanced version could be worn as a jacket.

To build the device, the team turned to a phase-changing material that’s similar to wax but with more complex properties. The melting point of the material is 30 degrees Celsius (roughly 86 degrees F), the same temperature as the surface temperature of human skin. If the temperature on the outside of the device is higher than that, the material will melt and stabilize, insulating the wearer; if colder, it will slowly solidify, still acting as an insulating layer.

The team, led by UC San Diego mechanical and aerospace engineering professor Renkun Chen, detailed their work in a recent issue of the journal

Advanced Functional Materials

.

At the technology’s core are materials that can create heating or cooling effects when the ambient temperature changes, and flexible electronics that can be embedded into clothing. The outside layer of the device is driven by a technology that Chen and colleagues detailed in a paper in

Science Advances

in May 2019. It is made of thermoelectric alloys—materials that use electricity to create a temperature difference—sandwiched between stretchy elastomer sheets. It is powered by a battery and controlled by a wireless circuit board. The device physically cools or heats to a temperature that the wearer chooses.

Current state of the art heat camouflage technology consists of a surface coating that changes how much heat clothing emits at the surface. The coating absorbs the heat from the wearer’s body and reflects only enough energy to match the ambient temperature. However, the coating only works at a predetermined temperature. If the ambient temperature rises or falls, it no longer works.

The researchers’ biggest challenge now is to scale up the technology. Their goal is to create a jacket with the technology built-in, but under current conditions, the garment would weigh 2 kilograms (about 4.5 lbs.), be about 5 millimeters thick and only function for one hour. The team will be looking to find lighter, thinner materials so the garment could weigh two or three times less.

The work was supported by the Advanced Research Project Agency and by a UC San Diego start up grant. It work was performed in part at the San Diego Nanotechnology Infrastructure (SDNI) at UC San Diego, a member of the National Nanotechnology Coordinated Infrastructure, which is supported by the National Science Foundation.

An Adaptive and Wearable Thermal Camouflage Device

Sahngki Hong and Renkun Chen, University of California San Diego

Sunmi Shin  National University of Singapore

West Virginia Couple’s Violent Robbery Spree Thwarted by FBI, Local Partners

Robbers Who Targeted Elderly Sentenced

In 2018, a 74-year-old Tennessee woman was attacked in her home by a pair of robbers who ransacked her house and stole her sense of safety.

Days later, a 72-year-old Tennessee man with dementia was attacked outside his home by the same assailants. They forced him inside and threw him down a stairwell after robbing him of a few possessions. Among the items stolen was a bomber jacket from the man’s service in Vietnam. It was an irreplaceable keepsake that investigators never found.

In all, Joshua Small and his girlfriend, Joni Johnson, robbed—and in some cases violently assaulted—seven senior citizens in West Virginia, Virginia, and Tennessee during a short period in the summer of 2018. In several cases, they subdued their victims by punching or hitting them and then tying them up while they ransacked their homes. The robbers held some of their victims at gunpoint or threatened them with guns.

The incidents shook the small, quiet towns where they took place.

“One victim’s son told us, ‘This is a small town. Everyone here knows me or my dad,’” said Special Agent Wesley Leatham, who investigated this case out of the FBI’s Knoxville Field Office along with FBI Task Force Officer Mark Webber of the Knox County Sheriff’s Department. “It really caused a lot of worry and concern in these communities.”

A break in the case came when a tipster saw a couple driving a rental car that matched the description of the robbers’ car and told local police. Pawn shop employees also confirmed that Small had been seen pawning stolen jewelry and other items.

Investigators found overwhelming evidence against the couple once they were identified, including incriminating evidence on their cell phones. Several victims also identified Johnson and Small based on photos.

The couple lived in West Virginia, and they used Small’s employer, a family paving business, to find some of their elderly victims. In other cases, investigators aren’t certain how the robbers targeted their victims, but they were all in their 70s, 80s, or 90s.

“Everyone really wanted to see justice for these victims, especially given their ages and the level of violence they suffered.”

Wesley Leatham, special agent, FBI Knoxville

With multiple sheriffs’ offices involved, the FBI played a key coordinating role. The Bureau also brought resources to the case, including the ability to press federal charges.

“We had great local partners in this case,” Leatham said. “Everybody came together with outstanding coordination. Everyone really wanted to see justice for these victims, especially given their ages and the level of violence they suffered.”

In July 2019, the couple was convicted of kidnapping charges. In January, Small was sentenced to 30 years in federal prison, and Johnson was sentenced to 25 years.

Investigators hope the outcome brought some closure to the victims and communities that were traumatized. One victim died before the trial and some others were unable to travel to it, but their relatives gave powerful impact statements.

“We’ve heard from the victims’ families since then that this has destroyed their sense of safety. They’re constantly checking the door to make sure it’s locked. Visitors have to call before they come over,” Leatham said. “It’s really had a lasting effect on a lot of people.”

Resources

Joshua Small and Joni Amber Johnson Sentenced for Kidnapping Elderly Victims

Temple’s Dr. Silvia Fossati Awarded $500,000 Grant for Alzheimer’s Disease Drug Discovery Research

(Philadelphia, PA) – Silvia Fossati, PhD,

Associate Professor of Pharmacology and Associate Director of the Alzheimer’s Center at Temple at the Lewis Katz School of Medicine, has been awarded a two-year $500,000 grant from The Edward N. and Della L. Thome Memorial Foundation, Bank of America, N.A., Trustee, as part of the Foundation’s Awards Program in Alzheimer’s Disease Drug Discovery Research.

Dr. Fossati, the principal investigator on the grant, will work with co-investigator

Marc Ilies, PhD,

Professor in the Department of Pharmaceutical Sciences at the Temple University School of Pharmacy, to develop a new Alzheimer’s-specific version of an already-existing drug family called carbonic anhydrase inhibitors, which are approved by the U.S. Food and Drug Administration (FDA) to treat conditions such as glaucoma and high-altitude sickness.

Previous studies in Dr. Fossati’s Lab showed that these drugs were effective in cell and animal models at targeting certain features of Alzheimer’s disease, including mitochondrial dysfunction, amyloid protein build-up, and inflammation.

Research has suggested that chronic inflammation in the brain may be due to the build-up of cells that normally free the organ of debris, waste and protein collections – including amyloid protein. When amyloid protein deposits in abnormal levels in the brain, it can disrupt cell function and communication pathways. Elevated levels can also be a factor in abnormalities of the mitochondria – the energy-generating batteries of cells – and in damaging the brain vasculature (its blood vessels). Collectively, these can eventually contribute to cognitive dysfunction, including impairments in memory and learning – hallmarks of Alzheimer’s disease.

Ideally, Dr. Fossati and Dr. Ilies’ drug would target these characteristics, as currently available carbonic anhydrase inhibitors do, but would better infiltrate the brain and cause fewer side effects.

The drug would be tested in cell and animal models of Alzheimer’s disease first and then potentially in human clinical trials in two to three years.

“Since carbonic anhydrase inhibitors have already been approved by the FDA and have demonstrated promising results, we are hopeful that we will be able to tailor what is currently available on the market to specifically target Alzheimer’s disease,” Dr. Fossati said. “We are so thankful that the foundation sees such promise in our work and has chosen to recognize us with this grant.”

The Edward N. and Della L. Thome Memorial Foundation, Bank of America, N.A., Trustee, which was established in 2002 by Robert P. Thome to honor the memory of his parents, provides funding in two areas – support for the dignified treatment of older adults and support for medical research on diseases affecting older adults. The medical research division alternates between funding research on macular degeneration and Alzheimer’s disease.

About Temple Health

Temple University Health System (TUHS) is a $2.2 billion academic health system dedicated to providing access to quality patient care and supporting excellence in medical education and research. The Health System consists of Temple University Hospital (TUH)

;

TUH-Episcopal Campus; TUH-Jeanes Campus; TUH-Northeastern Campus; The Hospital of Fox Chase Cancer Center and Affiliates, an NCI-designated comprehensive cancer center; Temple Transport Team, a ground and air-ambulance company; Temple Physicians, Inc., a network of community-based specialty and primary-care physician practices; and Temple Faculty Practice Plan, Inc., TUHS’s physician practice plan comprised of more than 500 full-time and part-time academic physicians in 20 clinical departments. TUHS is affiliated with the Lewis Katz School of Medicine at Temple University.

Temple Health refers to the health, education and research activities carried out by the affiliates of Temple University Health System (TUHS) and by the Katz School of Medicine. TUHS neither provides nor controls the provision of health care. All health care is provided by its member organizations or independent health care providers affiliated with TUHS member organizations. Each TUHS member organization is owned and operated pursuant to its governing documents.

It is the policy of Temple University Health System that there shall be no exclusion from, or participation in, and no one denied the benefits of, the delivery of quality medical care on the basis of race, ethnicity, religion, sexual orientation, gender, gender identity/expression, disability, age, ancestry, color, national origin, physical ability, level of education, or source of payment.