Studies Supported by The ALS Assn. Highlight Discovery Around Common ALS Gene Mutation

WASHINGTON, Aug. 26, 2015 /PRNewswire-USNewswire/ — In today\’s issue of Nature, two new studies funded in part by The ALS Association both highlight an important new discovery around the C9orf72 mutation, the most common genetic defect associated with amyotrophic lateral sclerosis (ALS). Both studies emphasize that a key driver of the development of ALS due to this mutation is an export-import imbalance between the cell\’s nucleus and its non-nuclear portion, or cytoplasm.