Within the intricate biochemical networks that sustain cellular vitality, few molecules occupy as central a position as nicotinamide adenine dinucleotide (NAD+). Although NAD+ itself is not a peptide, contemporary biochemical discourse increasingly refers to “NAD+ peptide systems” when describing peptide-regulated enzymes and signaling pathways whose catalytic or regulatory activity depends upon intracellular NAD+ availability. In this context, NAD+ is believed to function as a redox cofactor, a substrate for post-translational modifications, and a metabolic signal integrator. The peptide components of NAD+-dependent systems—most prominently the sirtuin family and poly(ADP-ribose) polymerases—form a regulatory architecture that research indicates may coordinate genomic stability, energy metabolism, circadian rhythm alignment, and adaptive stress responses within the organism.
Continue reading “NAD+ Peptide Systems: Metabolic Architecture and Emerging Research”Category: NEWS
Sherrill Administration Urges Public to Voluntarily Conserve Water
The Sherrill Administration today urged the public to continue voluntarily conserving water as the statewide Drought Warning remains in place entering the warmer months, a time when demand for water for lawns, landscaping and gardening increases across New Jersey.
I urge everyone to join us in spreading awareness about the importance of conserving water.” “The Department of Environmental Protection continues to closely monitor drought indicators and water supplies across New Jersey to avoid the possibility of mandatory restrictions,” said DEP Acting Commissioner Ed Potosnak. “Simple steps such as limiting lawn watering to two days a week and hand-watering shrubs and flowers can go a long way in stretching water supplies.” “New Jersey is experiencing a chronic water supply drought, the scale of which we haven’t seen in more than twenty years,” added State Geologist Steven Domber. “The indicators that we track closely are showing persistently dry conditions. With uncertainty for rainfall in the coming months, we need residents to conserve water today, to ensure we have enough to sustain our needs over the summer.” Water Supply Indicators The DEP continues to closely monitor current water supply indicators, which include precipitation, stream flows, reservoir levels, ground water levels, and water demand, to keep the public, local governments, and water systems informed of conditions and potential future actions.
In addition, the DEP continues to coordinate with water systems to ensure they are using all available sources to increase supplies for the warmer months. (Municipalities or water utilities may require additional restrictions depending upon local water supply conditions.)The DEP uses a four-tiered system to keep the public apprised of water supply conditions: Normal, Watch, Warning and Emergency. Under the current Drought Warning, residents are strongly urged to voluntarily conserve water. If conditions do not improve, the next step could be the declaration of a Drought Emergency, which carries mandatory restrictions. The last statewide drought emergency was declared in March 2002 and lifted in January 2003. Drought Conditions by the Numbers New Jersey has experienced eight consecutive months of below-normal rainfall and remains under a drought warning issued Dec. 5, 2025. The state has experienced below normal precipitation for 20 of the last 24 months since September 2024.
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Rowan’s Rothwein, Corkhill & Delaney Earn Top NJAC Honors; Six Named All-Conference
Rowan’s Madison Rothwein was named the 2026 NJAC Midfielder of the Year and Leah Corkhill was selected as the Defensive Player of the Year as the conference announced its annual awards. Head coach Lindsay Delaney and staff were named the Coaching Staff of the Year with Elaina Corson, Fiona Lockhart, Alexis Lowry and Jenna O’Neill joining Rothwein and Corkhill on the All-Conference Team.
Continue reading “Rowan’s Rothwein, Corkhill & Delaney Earn Top NJAC Honors; Six Named All-Conference”Brad Keselowski Headlines Dover Motor Speedway Open House
Dover Motor Speedway welcomed an enthusiastic crowd of hundreds of fans Thursday afternoon as 2012 NASCAR Cup Series champion Brad Keselowski headlined a special Open House event at The Monster Mile, previewing the upcoming NASCAR All-Star Weekend and kicking off the NXL Paintball Mid-Atlantic Open happening on property at Dover Motor Speedway this weekend.
Fans were invited inside the Speedway to walk the track, visit Victory Lane and participate in a live Q&A session with Keselowski on the famous Monster Monument. The Open House also coincided with the opening day of the NXL Paintball Mid-Atlantic Open, bringing a different kind of high-speed action to the Speedway. Keselowski joined in on the fun, taking part in paintball activities, including coaching a team and even shooting some paintballs at Tanner Hollis, Dover Motor Speedway’s manager of marketing.
Continue reading “Brad Keselowski Headlines Dover Motor Speedway Open House”Governor Sherrill Announces Online Application for Permitting Dashboard Pilot
Governor Mikie Sherrill announced a call for submissions for the pilot phase of the Permitting Dashboard on her 100th day in office, the first public-facing tool of its kind in New Jersey that will help streamline and bring greater transparency to the state’s permitting process. This is part of a whole-of-government effort to reform the state’s permitting system to save businesses and residents time and money.
The pilot will solicit applications from energy, commercial, and multi-family housing projects that have recently submitted—or are about to submit—permit applications to the New Jersey Department of Environmental Protection, New Jersey Department of Transportation, and/or New Jersey Department of Community Affairs. Up to 10 projects will be randomly selected from this pool for the pilot, allowing them to track the progress of their cross-agency permits in one place.
HUD Moving Forward on Bold Homelessness Reform
HUD is announcing that homelessness-related service providers across the nation can expect the 2026 Continuum of Care (CoC) Notice of Funding Opportunity (NOFO) to be published by June 1, 2026. Further, applicants can expect awards to be made by December 1, 2026. The CoC Program is a national competition designed to promote community-wide efforts to reduce homelessness and optimize self-sufficiency.
As the number of people living on our streets remains at crisis levels, HUD is committed to reforming its homelessness programs. The status quo of “housing first” and “harm reduction” has failed at great cost to those suffering on our streets and to working American taxpayers.
Continue reading “HUD Moving Forward on Bold Homelessness Reform”Rocky Lands a New Punch at the Philadelphia Museum of Art
In Philly, all roads lead to Rocky, one way or another.
Philly’s favorite fictional son has sparked spin-offs, podcasts, bus tours, generations of fandoms and, now, a major exhibition at the city’s premier art institution.
But Rising Up: Rocky and the Making of Monuments goes beyond Sylvester Stallone’s Oscar Award-winning franchise.
Continue reading “Rocky Lands a New Punch at the Philadelphia Museum of Art “Joan Pierce, 83, of Woodbury
On April 30, 2026, at the age of 83. (nee Murphy) Of Woodbury. Formerly of Gloucester City. Predeceased by her parents, Frank and Beatrice Murphy (nee Keown); her daughter, Denise Madison; and siblings, Frank Murphy and Eileen Giusti. Survived by her sons and their families, Alfred Pierce, David Pierce (Christine) and Wayne Pierce (Jennifer); 6 grandchildren; brother, Stephen Murphy (Angela) and sister, Bernice Wentz.(Lewis) and her special niece Theresa
Joan was raised in Gloucester City, NJ and was a proud graduate of Gloucester Catholic High School class of 1961.
Continue reading “Joan Pierce, 83, of Woodbury”Gloucester City Spring Hydrant Flushing
Hydrant flushing to begin on May 4 at 7:30 am.
Travelers Aged 30 and Under Save $20 on New TSA PreCheck® Membership
Limited time offer for the month of May
WASHINGTON – Just in time for the start of summer travel and the college and high school graduation seasons, the Transportation Security Administration (TSA) is launching a limited-time “$20 Take Off” promotion for new TSA PreCheck® applicants age 30 and under. From May 1 to May 31, eligible travelers can save $20 on their first five-year membership.
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